The Double Marker Test is a prenatal screening test conducted during the first trimester of pregnancy to assess the risk of chromosomal abnormalities in the developing fetus. It plays a vital role in early detection of conditions like Down syndrome (Trisomy 21), Trisomy 18, and Trisomy 13, giving expecting parents valuable insight into their baby’s health.
What is the Double Marker Test?
This test is part of the first-trimester screening, typically performed between 9 to 13 weeks of pregnancy. It measures the levels of two specific substances in the mother’s blood:
- Free Beta-human chorionic gonadotropin (β-hCG) – A hormone produced during pregnancy.
- Pregnancy-associated plasma protein A (PAPP-A) – A protein associated with the development of the placenta.
These markers are evaluated in combination with ultrasound findings (nuchal translucency scan) and maternal age to determine the likelihood of chromosomal disorders.
Why is the Double Marker Test Done?
This test is usually recommended for:
- Women above the age of 35
- Those with a family history of genetic disorders
- Pregnancies through IVF
- Pregnant women who want early risk assessment for chromosomal abnormalities
Early detection allows couples to make informed decisions and opt for further diagnostic tests like Non-Invasive Prenatal Testing (NIPT) or amniocentesis, if necessary.
Double Marker Test Procedure
The procedure is simple and non-invasive. A blood sample is drawn from the pregnant woman, typically between the 9th and 13th week of gestation. The blood is tested in a lab for the two markers mentioned earlier. The results are then interpreted using specialized software that calculates the risk factor based on various inputs including age, weight, and gestational age.
How to Read Double Marker Test Results
- Screen Positive (High Risk): Suggests a higher chance of the baby having a chromosomal disorder. Further diagnostic testing is recommended.
- Screen Negative (Low Risk): Indicates a lower likelihood of abnormalities, but it doesn’t guarantee the absence of issues.
It’s important to remember that the Double Marker Test is a screening test, not a diagnostic one. It cannot confirm the presence of a disorder but helps determine whether further testing is needed.
Double Marker Test Price in India
The cost of a Double Marker Test in India ranges from ₹2,000 to ₹4,500, depending on the city and laboratory. While pricing may vary, choosing a trusted diagnostic provider ensures accurate results and timely reporting.
Get Tested with Redcliffe Labs
At Redcliffe Labs, we provide accurate and affordable Double Marker Testing with free home sample collection in over 220+ cities. Our NABL and ISO-certified labs ensure high-quality testing with fast turnaround times. You can book the test online, and results are delivered digitally, helping you and your doctor make informed decisions quickly.
